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  "Package": "grouprar",
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  "Title": "Group Response Adaptive Randomization for Clinical Trials",
  "Version": "0.2.0",
  "Date": "2026-10-08",
  "Authors@R": "c(\nperson(given=\"Guannan\", family=\"Zhai\", email=\"guannanzhai1996@gmail.com\", role=c(\"aut\",\"cre\")),\nperson(given=\"Feifang\", family=\"Hu\", email=\"feifang@gwu.edu\", role=c(\"aut\",\"ths\"))\n)",
  "Description": "Implements group response-adaptive randomization\nprocedures, which include standard (non-group)\nresponse-adaptive randomization methods as special cases. The\npackage also handles delayed and missing responses, which\nbroadens its use in real-world trials. It offers functions for\nsimulating a variety of response-adaptive randomization\nprocedures, to help guide the choice of design for a clinical\ntrial, including the doubly adaptive biased coin design and the\nmulti-arm efficient randomized adaptive design (ERADE), k-arm\noptimal target allocations, group sequential monitoring, and a\nfunction that computes allocation probabilities for an ongoing\ntrial. For details of the methods and algorithms, see the\nfollowing references: Wei, L. J. (1979)\n<doi:10.1214/aos/1176344614>; Wei, L. J. and Durham, S. (1978)\n<doi:10.1080/01621459.1978.10480109>; Durham, S. D., Flournoy,\nN. and Li, W. (1998) <doi:10.2307/3315771>; Ivanova, A.,\nRosenberger, W. F., Durham, S. D. and Flournoy, N. (2000)\n<https://www.jstor.org/stable/25053121>; Bai, Z. D., Hu, F. and\nShen, L. (2002) <doi:10.1006/jmva.2001.1987>; Ivanova, A.\n(2003) <doi:10.1007/s001840200220>; Hu, F. and Zhang, L. X.\n(2004) <doi:10.1214/aos/1079120137>; Hu, F. and Rosenberger, W.\nF. (2006, ISBN:978-0-471-65396-7); Zhang, L. X., Chan, W. S.,\nCheung, S. H. and Hu, F. (2007)\n<https://www.jstor.org/stable/26432528>; Zhang, L. and\nRosenberger, W. F. (2006)\n<doi:10.1111/j.1541-0420.2005.00496.x>; Hu, F., Zhang, L. X.,\nCheung, S. H. and Chan, W. S. (2008)\n<doi:10.1002/cjs.5550360404>; Tymofyeyev, Y., Rosenberger, W.\nF. and Hu, F. (2007) <doi:10.1198/016214506000000906>; Hu, F.,\nZhang, L. X. and He, X. (2009) <doi:10.1214/08-AOS655>; Zhu, H.\nand Hu, F. (2010) <doi:10.1214/10-AOS796>; Zhai, G., Li, Y.,\nZhang, L. and Hu, F. (2024) <doi:10.1002/sim.10220>; Alkhnefr,\nN., Hu, F. and Zhai, G. (2025) <doi:10.1177/09622802251362644>.",
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