Package: grouprar
Type: Package
Title: Group Response Adaptive Randomization for Clinical Trials
Version: 0.2.0
Date: 2026-10-08
Authors@R: c(
    person(given="Guannan", family="Zhai", email="guannanzhai1996@gmail.com", role=c("aut","cre")), 
    person(given="Feifang", family="Hu", email="feifang@gwu.edu", role=c("aut","ths"))
    )
Description: Implements group response-adaptive randomization
        procedures, which include standard (non-group)
        response-adaptive randomization methods as special cases. The
        package also handles delayed and missing responses, which
        broadens its use in real-world trials. It offers functions for
        simulating a variety of response-adaptive randomization
        procedures, to help guide the choice of design for a clinical
        trial, including the doubly adaptive biased coin design and the
        multi-arm efficient randomized adaptive design (ERADE), k-arm
        optimal target allocations, group sequential monitoring, and a
        function that computes allocation probabilities for an ongoing
        trial. For details of the methods and algorithms, see the
        following references: Wei, L. J. (1979)
        <doi:10.1214/aos/1176344614>; Wei, L. J. and Durham, S. (1978)
        <doi:10.1080/01621459.1978.10480109>; Durham, S. D., Flournoy,
        N. and Li, W. (1998) <doi:10.2307/3315771>; Ivanova, A.,
        Rosenberger, W. F., Durham, S. D. and Flournoy, N. (2000)
        <https://www.jstor.org/stable/25053121>; Bai, Z. D., Hu, F. and
        Shen, L. (2002) <doi:10.1006/jmva.2001.1987>; Ivanova, A.
        (2003) <doi:10.1007/s001840200220>; Hu, F. and Zhang, L. X.
        (2004) <doi:10.1214/aos/1079120137>; Hu, F. and Rosenberger, W.
        F. (2006, ISBN:978-0-471-65396-7); Zhang, L. X., Chan, W. S.,
        Cheung, S. H. and Hu, F. (2007)
        <https://www.jstor.org/stable/26432528>; Zhang, L. and
        Rosenberger, W. F. (2006)
        <doi:10.1111/j.1541-0420.2005.00496.x>; Hu, F., Zhang, L. X.,
        Cheung, S. H. and Chan, W. S. (2008)
        <doi:10.1002/cjs.5550360404>; Tymofyeyev, Y., Rosenberger, W.
        F. and Hu, F. (2007) <doi:10.1198/016214506000000906>; Hu, F.,
        Zhang, L. X. and He, X. (2009) <doi:10.1214/08-AOS655>; Zhu, H.
        and Hu, F. (2010) <doi:10.1214/10-AOS796>; Zhai, G., Li, Y.,
        Zhang, L. and Hu, F. (2024) <doi:10.1002/sim.10220>; Alkhnefr,
        N., Hu, F. and Zhai, G. (2025) <doi:10.1177/09622802251362644>.
License: GPL (>= 2)
Imports: extraDistr, stats
Suggests: testthat (>= 3.1.5)
Config/testthat/edition: 3
Depends: R (>= 3.6.0)
Encoding: UTF-8
NeedsCompilation: no
Packaged: 2026-10-09 10:36:15 UTC; root
Author: Guannan Zhai [aut, cre], Feifang Hu [aut, ths]
Maintainer: Guannan Zhai <guannanzhai1996@gmail.com>
Repository: https://neptune555.r-universe.dev
Date/Publication: 2026-10-09 09:17:39 UTC
RemoteUrl: https://github.com/cran/grouprar
RemoteRef: HEAD
RemoteSha: 450af664b350b6346ef2c89c403cca70fe05daf5